Cypionic acid

Cypionic acid
Names
	IUPAC name 3-Cyclopentylpropanoic acid
	Other names 3-Cyclopentylpropionic acid; Cypionate; Cipionate
Identifiers
CAS Number	140-77-2
ChemSpider	8487
Jmol 3D model	Interactive image
PubChem	8818
	InChI InChI=1S/C8H14O2/c9-8(10)6-5-7-3-1-2-4-7/h7H,1-6H2,(H,9,10) Key: ZRPLANDPDWYOMZ-UHFFFAOYSA-N ; InChI=1/C8H14O2/c9-8(10)6-5-7-3-1-2-4-7/h7H,1-6H2,(H,9,10) Key: ZRPLANDPDWYOMZ-UHFFFAOYAK ;
	SMILES O=C(O)CCC1CCCC1 ;
Properties
Chemical formula	C8H14O2
Molar mass	142.20 g·mol−1
Density	0.996 g/mL
Melting point	130 to 132 °C (266 to 270 °F; 403 to 405 K) (12 mmHg)
Vapor pressure	{{{value}}}
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	Infobox references

Cypionic acid is a carboxylic acid with the molecular formula C₈H₁₄O₂. Its salts and esters are known as cypionates or cipionates.

The primary use of cypionic acid is in pharmaceutical formulations. Cypionic acid is used to prepare ester prodrugs which have increased half-lives relative to the parent compound. The lipophilicity of the cypionate group allows the prodrug to be sequestered in fat depots after intramuscular injection.^[2] The ester group is slowly hydrolyzed by metabolic enzymes, releasing steady doses of the active ingredient. Examples include testosterone cypionate, estradiol cypionate, hydrocortisone cypionate, and oxabolone cypionate.

References

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