BRIP1
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Fanconi anemia group J protein is a protein that in humans is encoded by the BRCA1-interacting protein 1 (BRIP1) gene.[1][2][3]
The protein encoded by this gene is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1). The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). This gene may be a target of germline cancer-inducing mutations.[3]
This protein also appears to be important in ovarian cancer where it seems to act as a tumor suppressor.[4]
Interactions
BRIP1 has been shown to interact with BRCA1.[5][6][7][8][9][10]
References
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