Nupapillomavirus
| Nupapillomavirus | |
|---|---|
| Virus classification | |
| Group: |
Group I (dsDNA)
|
| Family: | |
| Genus: |
Nupapillomavirus
|
| Type Species | |
|
|
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Nupapillomavirus is a genus of viruses, in the family Papillomaviridae. Human serve as natural hosts. There is currently only one species in this genus: the type species Nupapillomavirus 1. Diseases associated with this genus include: facial warts. It has also been detected in some skin carcinomas and premalignant keratoses.[1][2]
Taxonomy
Group: dsDNA
-
Family: Papillomaviridae
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Genus: Nupapillomavirus
- Nupapillomavirus 1
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Structure
Viruses in Nupapillomavirus are non-enveloped, with icosahedral geometries, and T=7 symmetry. The diameter is around 52-55 nm. Genomes are circular, around 8kb in length.[1]
| Genus | Structure | Symmetry | Capsid | Genomic Arrangement | Genomic Segmentation |
|---|---|---|---|---|---|
| Nupapillomavirus | Icosahedral | T=7 | Non-Enveloped | Circular | Monopartite |
Life Cycle
Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear envelope breakdown. Human serve as the natural host. Transmission routes are contact.[1]
| Genus | Host Details | Tissue Tropism | Entry Details | Release Details | Replication Site | Assembly Site | Transmission |
|---|---|---|---|---|---|---|---|
| Nupapillomavirus | Humans | Epithelial: mucous; epithelial: skin | Cell receptor endocytosis | Lysis | Nucleus | Nucleus | Contact |
