Finegoldia
Finegoldia | |
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Peptoniphilaceae
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Finegoldia
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Finegoldia are gram positive anaerobic cocci of the class clostridia, with Finegoldia magna being the type species.[1] Finegoldia magna was formerly known, along with several other gram positive anaerobic cocci (GPACs), as Peptostreptococcus magnus but was moved into its own genus in 1999.[2][3] The name is in honor of Sydney M. Finegold, an American microbiologist, while magna is latin for large.[1] It is an opportunistic human pathogen that normally colonizes skin and mucous membranes.[4] It is often seen in biofilms on chronic ulcers such as in diabetic foot or decubitus ulcers.[3] Most surveys have found it to be susceptible to penicillins, carbapenems and metronidazole, though resistant strains have been identified.[5] Resistance to clindamycin is common and has been seen in over 10% of isolates in the US.[3][6] One review stated that "the combination of diminished antimicrobial susceptibility, its prevalence, and the described virulence factors gives F. magna a special position among the GPAC."[5]
References
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