3β-Dihydroprogesterone
From Infogalactic: the planetary knowledge core
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| Names | |
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| IUPAC name
3β-Hydroxy-4-pregnen-20-one
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| Other names
3β-Dihydroprogesterone
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| Properties | |
| C21H32O2 | |
| Molar mass | 316.47758 g/mol |
| Vapor pressure | {{{value}}} |
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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| Infobox references | |
3β-Dihydroprogesterone (3β-DHP), also known as 3β-hydroxy-4-pregnen-20-one, is an endogenous steroid.[1] It is biosynthesized by 3β-hydroxysteroid dehydrogenase from progesterone. Unlike 3α-dihydroprogesterone, 3β-DHP does not act as a positive allosteric modulator of the GABAA,[1] which is in accordance with the fact that other 3β-hydroxylated progesterone metabolites such as isopregnanolone and epipregnanolone similarly do not act as potentiators of this receptor and instead inhibit it as well as reverse the effects of potentiators like allopregnanolone.[2]
See also
References
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