Alpha operon ribosome binding site

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Alpha operon ribosome binding site
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Predicted secondary structure and sequence conservation of Alpha_RBS
Identifiers
Symbol Alpha_RBS
Rfam RF00140
Other data
RNA type Cis-reg
Domain(s) Bacteria
SO 0000233

The alpha operon ribosome binding site in bacteria is surrounded by this complex pseudoknotted RNA structure. Translation of the mRNA produces 4 ribosomal protein products, one of which (S4) acts as a translational repressor by binding to the nested pseudoknot region. The mechanism of repression is thought to involve a conformational switch in the pseudoknot region and ribosome entrapment.[1]

References

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External links

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