Ambidensovirus

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Ambidensovirus
Virus classification
Group:
Group II (ssDNA)
Order:
Unassigned
Family:
Subfamily:
Genus:
Ambidensovirus
Type species
Lepidopteran ambidensovirus 1

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The virus genus Ambidensovirus belongs to the Densovirinae subfamily which belongs to the Parvoviridae family. The viruses of this genus are single-stranded DNA viruses. This genus infects invertebrates, including crustaceans and insects. There are currently six species in this genus including the type species Lepidopteran ambidensovirus 1.[1][2]

Taxonomy

Group: ssDNA

Order: Unassigned

[2]

Structure

Virions consist of non-enveloped capsids that have a round appearance and display icosahedral symmetry.[3] The virions each have an isometric (and therefore spherical) nucleocapsid with a diameter of either 18–22 nm or 20–26 nm.[3] Sixty capsomers are present in each capsid.[3] The structure of each capsomer is described as "a quadrilateral 'kite-shaped' wedge"; the surface is said to have a rough appearance with small projections.[3] The centre of capsids are sometimes visualised as appearing dark due to stain penetration in preparations where only a single species is retrieved. The virions do not appear to contain lipids. The buoyant density (in CsCl) of the virions is 1.4–1.44 g cm−3.[3]

Genus Structure Symmetry Capsid Genomic Arrangement Genomic Segmentation
Ambidensovirus Icosahedral T=1 Non-Enveloped Linear Segmented

Genome

Ambidensoviruses are non-enveloped and have icosahedral capsids with T=1 symmetry. They have non-segmented genomes that contain a single linear molecule of single-stranded DNA. The genome codes for structural proteins are about 5000 nucleotides in length and could either be negative-sense or positive-sense. Conserved nucleotide sequences of usually 120–300 or more nucleotides are present at the 3'-terminus and an inverted repeat of this could also be found at the 5'-terminus.[3]

Life Cycle

Viral replication is nuclear. Entry into the host cell is achieved by attachment to host receptors, which mediates clathrin-mediated endocytosis. Replication follows the rolling-hairpin model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. Insects serve as the natural host.[1]

Genus Host Details Tissue Tropism Entry Details Release Details Replication Site Assembly Site Transmission
Ambidensovirus Insects Variable Clathrin-mediated endocytosis uncertain Nucleus Nucleus Unknown

References

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  3. 3.0 3.1 3.2 3.3 3.4 3.5 Lua error in package.lua at line 80: module 'strict' not found.

External links