Carboxyfluorescein
From Infogalactic: the planetary knowledge core
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| Other names
6-FAM
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| Identifiers | |
3301-79-9  |
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| ChEBI | CHEBI:39073 |
| ChemSpider | 69262 |
| Jmol 3D model | Interactive image |
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| Properties | |
| C21H12O7 | |
| Molar mass | 376.32 g·mol−1 |
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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 verify (what is  ?) |
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Carboxyfluorescein is either of two fluorescent dyes with an excitation and emission of 492/517 nm, respectively. A carboxyfluorescein molecule is a fluorescein molecule with a carboxyl group added. They are commonly used as a tracer agents. The dyes are membrane-impermeant and can be loaded into cells by microinjection or scrape loading.[1] It can be incorporated into liposomes, and allow for the tracking of liposomes as they pass through the body. In addition, carboxyfluorescein has been used to track division of cells.[2]
Popular derivatives for cell tracing purposes are Carboxyfluorescein diacetate succinimidyl ester (CFDA-SE) and Carboxyfluorescein succinimidyl ester (CFSE).
