Carboxypeptidase B
From Infogalactic: the planetary knowledge core
carboxypeptidase B1 (tissue) | |
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Identifiers | |
Symbol | CPB1 |
Entrez | 1360 |
HUGO | 2299 |
OMIM | 114852 |
RefSeq | NM_001871 |
UniProt | P15086 |
Other data | |
EC number | 3.4.17.2 |
Locus | Chr. 3 q24 |
carboxypeptidase B2 (plasma) | |
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Identifiers | |
Symbol | CPB2 |
Entrez | 1361 |
HUGO | 2300 |
OMIM | 603101 |
RefSeq | NM_016413 |
UniProt | Q96IY4 |
Other data | |
Locus | Chr. 13 q14.11 |
carboxypeptidase B | |||||||||
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Identifiers | |||||||||
EC number | 3.4.17.2 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / EGO | ||||||||
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Carboxypeptidase B (EC 3.4.17.2, protaminase, pancreatic carboxypeptidase B, tissue carboxypeptidase B, peptidyl-L-lysine [L-arginine]hydrolase) is a carboxypeptidase that preferentially acts upon basic amino acids, such as arginine and lysine.[1][2][3][4] This serum enzyme is also responsible for rapidly metabolizing the C5a protein into C5a des-Arg, with one less amino acid.
References
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External links
- The MEROPS online database for peptidases and their inhibitors: M14.003
- Carboxypeptidase B at the US National Library of Medicine Medical Subject Headings (MeSH)