Cefozopran

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Cefozopran
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Systematic (IUPAC) name
(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)- 2-methoxyiminoacetyl]amino]-3-(imidazo[2,3-f]pyridazin- 4-ium-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0] oct-2-ene-2-carboxylate
Clinical data
AHFS/Drugs.com International Drug Names
Identifiers
CAS Number 113359-04-9 YesY
ATC code J01DE03 (WHO)
PubChem CID: 9571080
ChemSpider 7845546 N
UNII 1LG87K28LW YesY
KEGG D01052 YesY
ChEMBL CHEMBL1276663 N
Chemical data
Formula C19H17N9O5S2
Molecular mass 515.52 g/mol
  • O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)C(=N\OC)/c3nc(sn3)N)Cn5c4cccn[n+]4cc5)C([O-])=O
  • InChI=1S/C19H17N9O5S2/c1-33-24-11(14-23-19(20)35-25-14)15(29)22-12-16(30)28-13(18(31)32)9(8-34-17(12)28)7-26-5-6-27-10(26)3-2-4-21-27/h2-6,12,17H,7-8H2,1H3,(H3-,20,22,23,25,29,31,32)/b24-11-/t12-,17-/m1/s1 N
  • Key:QDUIJCOKQCCXQY-WHJQOFBOSA-N N
 NYesY (what is this?)  (verify)

Cefozopran (INN) is a fourth-generation cephalosporin.

Spectrum of bacterial susceptibility and resistance

Most of the strains of Stenotrophomonas maltophilia have developed resistance toward cefozopran.[1]

References

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