Cunninghamella

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Cunninghamella
Cunninghamella echinulata01.jpg
Cunninghamella echinulata
Scientific classification
Kingdom:
Order:
Family:
Genus:
Cunninghamella

Matr. (1903)
Type species
Cunninghamella africana
Matr. 1903
Synonyms[1]
  • Actinocephalum Saito (1905)
  • Muratella Bainier & Sartory (1913)
  • Saitomyces Ricker (1906)

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Cunninghamella is a genus of fungi in the order Mucorales, and the family Cunninghamellaceae.[2] The genus was circumscribed by French mycologist Alphonse Louis Paul Matruchot in 1903.[3]

Species

As of  2015, Index Fungorum lists 13 valid species of Cunninghamella:[4]

Uses

Members of this genus are often used in studies investigating the metabolism of drugs, because these species metabolize a wide range of drugs in manners similar to mammalian enzyme systems.[5] Many species are also capable of oxidizing polycyclic aromatic hydrocarbons, a class of stable organic molecules that tends to persist in the environment and contains many known carcinogenic and mutagenic compounds.[6]

The presence of a cytochrome P-450 has been demonstrated in C. bainieri.[7]

See also

References

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External links


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  2. Cunninghamella at the US National Library of Medicine Medical Subject Headings (MeSH)
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  7. Aryl hydrocarbon hydroxylase activity in the fungus Cunninghamella bainieri: Evidence for the presence of cytochrome P-450. J.P. Ferris, L.H. MacDonald, M.A. Patrie and M.A. Martin, Archives of Biochemistry and Biophysics, Volume 175, Issue 2, August 1976, pages 443-452, doi:10.1016/0003-9861(76)90532-4