Dulcin

Not to be confused with phyllodulcin.

For the sugar alcohol, see galactitol.

Dulcin

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Names
IUPAC name (4-Ethoxyphenyl)urea
Other names Sucrol; Valzin; Dulcine; Suesstoff
Identifiers
CAS Number	150-69-6 Y
ChemSpider	8663
Jmol 3D model	Interactive image
KEGG	C19415 Y
PubChem	9013
UNII	8U78KF577Z Y
InChI InChI=1S/C9H12N2O2/c1-2-13-8-5-3-7(4-6-8)11-9(10)12/h3-6H,2H2,1H3,(H3,10,11,12) Key: GGLIEWRLXDLBBF-UHFFFAOYSA-N InChI=1/C9H12N2O2/c1-2-13-8-5-3-7(4-6-8)11-9(10)12/h3-6H,2H2,1H3,(H3,10,11,12) Key: GGLIEWRLXDLBBF-UHFFFAOYAA
SMILES CCOC1=CC=C(C=C1)NC(=O)N
Properties
Chemical formula	C9H12N2O2
Molar mass	180.20 g/mol
Vapor pressure	{{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y verify (what is YN ?)
Infobox references

Dulcin is an artificial sweetener about 250 times sweeter than sugar discovered in 1884 by Joseph Berlinerbau. It was first mass-produced about seven years later. Despite the fact that it was discovered only five years after saccharin, it never enjoyed the latter compound’s market success. Still, it was an important sweetener of the early 20th century and had an advantage over saccharin in that it did not possess a bitter aftertaste.

Early medical tests marked the substance as safe for human consumption, and it was considered ideal for diabetics. However, an FDA study in 1951 raised many questions about its safety resulting in its removal from the market in 1954 after animal testing revealed unspecified carcinogenic properties. In Japan, poisoning accidents by dulcin occurred frequently, and use of dulcin was forbidden in 1969.

Dulcin is also known by the names sucrol and valzin.

Additional reading

• Hodges, L. 1973. Environmental pollution: a survey emphasizing physical and chemical principles. Holt, Rinehart and Winston Inc., New York.

• ズルチン標準品-Dulcin Standard (Japanese), Wako Pure Chemical Industries