FKBP3
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). FK506-binding protein 3 is a protein that in humans is encoded by the FKBP3 gene.[1][2][3]
Function
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.[3]
Interactions
FKBP3 has been shown to interact with YY1,[4] HDAC1,[4] Histone deacetylase 2[4] and Mdm2.[5]
References
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Further reading
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