GABRG1

Gamma-aminobutyric acid (GABA) A receptor, gamma 1
Identifiers
Symbols	GABRG1 ; DKFZp686H2042; MGC33838
External IDs	OMIM: 137166 MGI: 103156 HomoloGene: 22570 IUPHAR: 413 ChEMBL: 4044 GeneCards: GABRG1 Gene
Gene ontology Molecular function • GABA-A receptor activity • inhibitory extracellular ligand-gated ion channel activity • chloride channel activity • benzodiazepine receptor activity • GABA receptor binding Cellular component • integral component of plasma membrane • cell junction • chloride channel complex • neuron projection • synapse • postsynaptic membrane • GABA-A receptor complex Biological process • gamma-aminobutyric acid signaling pathway • synaptic transmission • regulation of membrane potential • response to drug • neurological system process • chloride transmembrane transport Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	2565	14405
Ensembl	ENSG00000163285	ENSMUSG00000001260
UniProt	Q8N1C3	Q9R0Y8
RefSeq (mRNA)	NM_173536	NM_010252
RefSeq (protein)	NP_775807	NP_034382
Location (UCSC)	Chr 4: 46.04 – 46.12 Mb	Chr 5: 70.75 – 70.84 Mb
PubMed search	[1]	[2]

Gamma-aminobutyric acid receptor subunit gamma-1 is a protein that in humans is encoded by the GABRG1 gene. The protein encoded by this gene is a subunit of the GABAA receptor.

Variants of this gene may be associated with alcohol dependence.

External links

• GABRG1 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)