JWH-116

JWH-116

Systematic (IUPAC) name
(2-ethyl-1-pentyl-1H-indol-3-yl)-1-naphthalenylmethanone
Clinical data
Legal status	CA: Schedule II UK: Class B
Identifiers
CAS Number	619294-64-3
ChemSpider	29341485
UNII	RKP962UAI3 Y
Chemical data
Formula	C26H27NO
Molecular mass	369.50 g/mol
SMILES CCCCCN1C2=CC=CC=C2C(=C1CC)C(=O)C3=CC=CC4=CC=CC=C43
InChI InChI=1S/C26H27NO/c1-3-5-10-18-27-23(4-2)25(22-15-8-9-17-24(22)27)26(28)21-16-11-13-19-12-6-7-14-20(19)21/h6-9,11-17H,3-5,10,18H2,1-2H3 Key:AQHPTHKEKSWGPO-UHFFFAOYSA-N

JWH-116 is a synthetic cannabinoid receptor ligand from the naphthoylindole family. It is the indole 2-ethyl derivative of related compound JWH-018. The binding affinity of JWH-116 for the CB₁ receptor is reported as K_i = 52 ± 5 nM.

See also

• JWH-018
• JWH-081