Mangostin

Mangostin

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Names
IUPAC names 3,6,8-Trihydroxy-2-methoxy-1,7- bis(3-methylbut-2-enyl)xanthen-9-one
Identifiers
CAS Number	6147-11-1 Y
ChEBI	CHEBI:67547 N
ChEMBL	ChEMBL323197 Y
ChemSpider	4444969 Y
Jmol 3D model	Interactive image
PubChem	5281650
InChI InChI=1S/C24H26O6/c1-12(2)6-8-14-16(25)10-19-21(22(14)27)23(28)20-15(9-7-13(3)4)24(29-5)17(26)11-18(20)30-19/h6-7,10-11,25-27H,8-9H2,1-5H3 Y Key: GNRIZKKCNOBBMO-UHFFFAOYSA-N Y InChI=1/C24H26O6/c1-12(2)6-8-14-16(25)10-19-21(22(14)27)23(28)20-15(9-7-13(3)4)24(29-5)17(26)11-18(20)30-19/h6-7,10-11,25-27H,8-9H2,1-5H3 Key: GNRIZKKCNOBBMO-UHFFFAOYAL
SMILES CC(=CCC1=C(C=C2C(=C1O)C(=O)C3=C(C(=C(C=C3O2)O)OC)CC=C(C)C)O)C
Properties
Chemical formula	C24H26O6
Molar mass	410.45 g/mol
Appearance	Yellow crystalline solid
Density	1.265 g/ml
Melting point	182 °C (360 °F; 455 K)
Vapor pressure	{{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Mangostin is a natural xanthonoid, a type of organic compound isolated from various parts of the mangosteen tree (Garcinia mangostana). It is a yellow crystalline solid with a xanthone core structure. Mangostin and a variety of other xanthones from mangosteen have been investigated for biological properties including antioxidant, anti-bacterial, anti-inflammatory, and anticancer activities. There are no positive correlations found as a result of this study. In animal studies, mangostin has been found to be a central nervous system depressant which causes sedation, decreased motor activity, and ptosis.

The rind of partially ripe mangosteen fruit yields mangostin and also the related compound β-mangostin. The rind of fully ripe fruits contains the xanthonoids gartanin, 8-disoxygartanin and normangostin. A derivative of mangostin, mangostin-3,6-di-O-glucoside, is a central nervous system depressant and causes a rise in blood pressure.