Mantle zone
From Infogalactic: the planetary knowledge core
Mantle zone | |
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![]() Image labeled in German, but "Mantel-zone" visible near center.
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Identifiers | |
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Anatomical terminology
[[[d:Lua error in Module:Wikidata at line 863: attempt to index field 'wikibase' (a nil value).|edit on Wikidata]]]
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The mantle zone (or just mantle) of a lymphatic nodule (or lymphatic follicle) is an outer ring of small lymphocytes surrounding a germinal center.[1]
It is also known as the "corona".[2]
It contains transient lymphocytes.[3]
It is the location of the lymphoma in mantle cell lymphoma.
Pathology
![](/w/images/thumb/4/40/Castleman_disease_-_intermed_mag.jpg/300px-Castleman_disease_-_intermed_mag.jpg)
Intermediate magnification micrograph of Castleman disease showing the characteristic expansion of the mantle zone. H&E stain.
Mantle zone expansion may be seen in benign, such as Castleman disease, and malignancy, i.e., Mantle cell lymphoma.
References
External links
- http://erl.pathology.iupui.edu/HISTO/LABE109.HTM
- Histology image: 07102loa – Histology Learning System at Boston University — "Lymphoid Tissues and Organs: lymph node, cortex and medulla"
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