Moco-II RNA motif
| Moco-II RNA | |
|---|---|
| 280px | |
| Consensus secondary structure of Moco-II RNAs | |
| Identifiers | |
| Symbol | Moco-II RNA |
| Rfam | RF01713 |
| Other data | |
| Domain(s) | Deltaproteobacteria |
The Moco-II RNA motif is a conserved RNA structure identified by bioinformatics.[1] However, only 8 examples of the RNA motif are known. The RNAs are potentially in the 5' untranslated regions of genes related to molybdenum cofactor (Moco), specifically a gene that encodes a molybdenum-binding domain and a nitrate reductase, which uses Moco as a cofactor. Thus the RNA might be involved in the regulation of genes based on Moco levels. Reliable predictions of Moco-II RNAs are restricted to deltaproteobacteria, but a Moco-II RNA might be present in a betaproteobacterial species. The Moco RNA motif is another RNA that is associated with Moco, and its complex secondary structure and genetic experiments have led to proposals that it is a riboswitch. However, the simpler structure of the Moco-II RNA motif (see diagram) is less typical of riboswitches. Moco-II RNAs are typically followed by a predicted rho-independent transcription terminator.
References
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External links
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