NRON
From Infogalactic: the planetary knowledge core
| ncRNA Repressor of NFAT (nuclear factor of activated T cells) | |
|---|---|
| 220px | |
| Predicted secondary structure and sequence conservation of NRON | |
| Identifiers | |
| Symbol | NRON |
| Rfam | RF00636 |
| Other data | |
| RNA type | Gene |
| Domain(s) | Eukaryota |
| SO | 0001263 |
NRON also known as ncRNA repressor of the nuclear factor of activated T cells is a non-coding RNA involved in repressing NFAT.[1] The function of this ncRNA was identified by a large-scale screen of 512 non-coding RNAs discovered in earlier EST sequencing projects.[2][3]
Each of the RNAs that were conserved between human and mouse were knocked down using shRNAs. The resulting cell-lines were screened for changes in activity of NFAT.
References
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