PDCD4
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Programmed cell death protein 4 is a protein that in humans is encoded by the PDCD4 gene.[1][2] It is one of the targets of an oncomiR, MIRN21.[3]
Function
This gene encodes a protein localized to the nucleus in proliferating cells. Expression of this gene is modulated by cytokines in natural killer and T cells. The gene product is thought to play a role in apoptosis but the specific role has not yet been determined. Two transcripts encoding different isoforms have been identified.[2]
Interactions
PDCD4 has been shown to interact with RPS13[4] and Ribosomal protein L5.[4]
References
Further reading
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