Redoxon
Redoxon is the name of the first artificially synthesized ascorbic acid (Vitamin C).[1] Redoxon was first marketed to the general public in 1934[2] – the first mass-manufactured synthetic vitamin in history.[3] It is now a brand owned by German pharmaceutical company Bayer and is sold world-wide.
The product was developed by a team headed by chemist Tadeusz Reichstein, who discovered a method of synthesizing 30-40 g of vitamin C from 100 g of glucose. This used an intermediate step of creating sorbose using an ingenious bacterial fermentation method discovered by a French researcher, Gabriel Bertrand. In this method, fruit flies were attracted to a mixture of wine, vinegar, yeast bouillon, and sorbitol, a substance easily chemically prepared from glucose. Flies which fed upon sorbitol as a major food subtrate excreted bacteria which were able to synthesize sorbose from sorbitol. Using the bacteria, within a few days, it was possible to create 50 grams of sorbose using this method, and it was then easy to synthesise ascorbic acid from this.[4]
Despite concern about using the wild strain of bacteria for fermentation-production of sorbose, the process was superior to a rival method of Szent-Gyorgyi which isolated Vitamin C from capsicum. After sale of the Reichstein process patent to Hoffmann-La Roche, this process became the basis of the corporation's large-scale production of vitamin C.[4]
The commercial tablets are compounded from ascorbic acid and sodium bicarbonate. When these are added to water, they react to produce sodium ascorbate, water and carbon dioxide, thus producing a pleasant effervescence.[5]
In addition to Redoxon vitamin C, Redoxon Vita Immune tablets are also produced. Each one contains:
Nutrient | Quantity |
---|---|
Vitamin C | 1000 mg |
Vitamin A | 2333 IU |
Vitamin B6 | 6.5 mg |
Vitamin B12 | 9.6 ug |
Vitamin D | 400 IU |
Vitamin E | 45 mg |
Folic Acid | 400 ug |
Zinc | 10 mg |
Selenium | 110 ug |
Copper | 900 ug |
Iron | 5 mg |
References
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