Saffold virus
Saffold virus | |
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Group IV ((+)ssRNA)
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Saffold virus |
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Saffold virus (SAFV) is a single-stranded RNA human virus belonging to the Picornaviridae family. Discovered in 2007, it is the first human virus in the Cardiovirus genus and may provide a link to the development of multiple sclerosis or other serious diseases in humans.[1]
Contents
Discovery
SAFV was discovered by Morris S. Jones in 2007 while working at the David Grant USAF Medical Center in the United States.[2] The virus was isolated from a stool sample taken in November 1981 from an 8-month-old female with fever of unknown origin.
This is the first human virus in the Cardiovirus family. Found to occur in high prevalence (>90%) among humans, by analogy SAFV may have effects similar to those observed in mouse TMEV-induced encephalomyelitis, in terms of catalyzing the development of human Multiple Sclerosis or other serious diseases because of infection early in life.[1] Much more study will be needed.
Strains
Nine strains of SAFV have been identified; these are named SAFV-1 through to SAFV-9.
See also
References
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