Small nucleolar RNA snR66

Small nucleolar RNA snR66
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Predicted secondary structure and sequence conservation of snosnR66
Identifiers
Symbol	snosnR66
Rfam	RF00477
Other data
RNA type	Gene; snRNA; snoRNA; CD-box
Domain(s)	Eukaryota
GO	0006396 0005730
SO	0000593

snoRNA snR66 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA snR66 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. snoRNA snR66 was initially discovered using a computational screen of the Saccharomyces cerevisiae genome.

External links

• Page for Small nucleolar RNA snR66 at Rfam
• Link to snR66 at the FournierLab's snoRNAdb.