Sulfamethizole

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Sulfamethizole
Systematic (IUPAC) name
250px
4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)- benzenesulfonamide
Clinical data
AHFS/Drugs.com	Micromedex Detailed Consumer Information
MedlinePlus	a682231
Pharmacokinetic data
Protein binding	98–99%
Biological half-life	3–8 hours

Identifiers
CAS Number	144-82-1^Y
ATC code	B05CA04 (WHO) D06BA04 J01EB02 S01AB01 QJ01EQ02 (WHO)
PubChem	CID: 5328
DrugBank	DB00576^Y
ChemSpider	5137^Y
UNII	25W8454H16^Y
KEGG	D00870^Y
ChEBI	CHEBI:9331^Y
ChEMBL	CHEMBL1191^Y
Chemical data
Formula	C₉H₁₀N₄O₂S₂
Molecular mass	270.333 g/mol
SMILES O=S(=O)(Nc1nnc(s1)C)c2ccc(N)cc2
InChI InChI=1S/C9H10N4O2S2/c1-6-11-12-9(16-6)13-17(14,15)8-4-2-7(10)3-5-8/h2-5H,10H2,1H3,(H,12,13)^Y Key:VACCAVUAMIDAGB-UHFFFAOYSA-N^Y

(verify)

Sulfamethizole is a sulfonamide antibiotic.

References

Tetracycline and derivatives	Demeclocycline Chlortetracycline Oxytetracycline Tetracycline
Others	Amphenicol: Chloramphenicol Aminoglycosides: Neomycin Gentamicin Amikacin Quinolone: Nadifloxacin Streptogramin: Virginiamycin Rifamycin: Rifaximin other: Fusidic acid Bacitracin Tyrothricin Mupirocin

Sulfonamides	Silver sulfadiazine Sulfathiazole Mafenide Sulfamethizole Sulfanilamide Sulfamerazine
Antivirals	Aciclovir Penciclovir Idoxuridine Edoxudine Imiquimod Resiquimod Podophyllotoxin Docosanol Tromantadine Inosine Lysozyme Ibacitabine Lysine
Other	Ingenol mebutate Metronidazole

Antifolates
(inhibits
purine metabolism,
thereby inhibiting
DNA and RNA synthesis)

Short- acting	Sulfaisodimidine Sulfamethizole Sulfadimidine Sulfapyridine Sulfafurazole Sulfanilamide Prontosil Sulfathiazole Sulfathiourea
Intermediate- acting	Sulfamethoxazole Sulfadiazine^# Sulfamoxole
Long- acting	Sulfadimethoxine Sulfadoxine Sulfalene Sulfametomidine Sulfametoxydiazine Sulfamethoxypyridazine Sulfaperin Sulfamerazine Sulfaphenazole Sulfamazone
Other/ungrouped	Sulfacetamide Sulfadicramide Sulfametrole

Combinations

2nd g.	Ciprofloxacin^# Ofloxacin Enoxacin^‡ Fleroxacin^‡ Lomefloxacin^‡ Nadifloxacin^‡ Norfloxacin^‡ Pefloxacin^‡ Rufloxacin^‡
3rd g.	Levofloxacin Balofloxacin^‡ Grepafloxacin^‡ Pazufloxacin^‡ Sparfloxacin^‡ Temafloxacin^‡ Tosufloxacin^‡
4th g.	Besifloxacin Gatifloxacin Finafloxacin Gemifloxacin Moxifloxacin Clinafloxacin^† Garenoxacin^‡ Prulifloxacin^‡ Sitafloxacin^‡ Trovafloxacin^‡/Alatrofloxacin^‡
Vet.	Danofloxacin Difloxacin Enrofloxacin Ibafloxacin Marbofloxacin Orbifloxacin Pradofloxacin Sarafloxacin

Newer non-fluorinated

Related (DG)

Nitro- imidazole derivatives	Metronidazole^# Tinidazole Ornidazole
Nitrofuran derivatives	Nitrofurantoin^# Furazolidone^‡ Nifurtoinol

RNA synthesis

Rifamycins/ RNA polymerase	Rifampicin^# Rifabutin Rifapentine Rifaximin

v t e Index of bacterial disease
Description	Bacteria classification Growth media
Disease	Gram-positive firmicutes Gram-positive actinobacteria Gram-negative proteobacteria Gram-negative non-proteobacteria Cholera Tuberculosis
Treatment	Antibiotics cell wall nucleic acid mycobacteria protein synthesis other Antibodies