Sulfafurazole

Sulfafurazole
Systematic (IUPAC) name
	4-amino-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzenesulfonamide
Clinical data
AHFS/Drugs.com	International Drug Names
MedlinePlus	a601049
Pregnancy; category	To be avoided within two months of term;
Legal status	℞ (Prescription only);
Routes of; administration	Oral
Pharmacokinetic data
Excretion	Excreted unchanged in urine
Identifiers
CAS Number	127-69-5
ATC code	J01EB05 (WHO) S01AB02 QJ01EQ05 (WHO)
PubChem	CID: 5344
DrugBank	DB00263
UNII	740T4C525W
KEGG	D00450
ChEMBL	CHEMBL453
Chemical data
Formula	C11H13N3O3S
Molecular mass	267.30 g/mol
	SMILES CC1=C(ON=C1C)NS(=O)(=O)C2=CC=C(C=C2)N ;
Physical data
Melting point	194 °C (381 °F)
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Sulfafurazole (INN, also known as sulfisoxazole) is a sulfonamide antibacterial with an oxazole substituent. It has antibiotic activity against a wide range of Gram-negative and Gram-positive organisms. It is sometimes given in combination with erythromycin (see erythromycin/Sulfafurazole) or phenazopyridine. It is used locally in a 4% solution or ointment.

Synthesis

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