TRIM3
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Tripartite motif-containing protein 3 is a protein that in humans is encoded by the TRIM3 gene.[1][2]
The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified.[2]
Interactions
TRIM3 has been shown to interact with Actinin alpha 4.[3]
References
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