Template:PBB/1524

Chemokine (C-X3-C motif) receptor 1
Identifiers
Symbols	CX3CR1 ; CCRL1; CMKBRL1; CMKDR1; GPR13; GPRV28; V28
External IDs	OMIM: 601470 MGI: 1333815 HomoloGene: 20350 IUPHAR: 74 ChEMBL: 4843 GeneCards: CX3CR1 Gene
Gene ontology Molecular function • chemokine receptor activity • protein binding • C-X3-C chemokine receptor activity Cellular component • plasma membrane • integral component of plasma membrane • neuronal cell body membrane • neuron projection • perinuclear region of cytoplasm Biological process • positive regulation of neuroblast proliferation • microglial cell activation involved in immune response • negative regulation of chronic inflammatory response to non-antigenic stimulus • chemotaxis • cellular defense response • cell adhesion • G-protein coupled receptor signaling pathway • memory • response to wounding • viral process • negative regulation of angiogenesis • cerebral cortex cell migration • negative regulation of cell migration • positive regulation of angiogenesis • macrophage chemotaxis • chemokine-mediated signaling pathway • cellular response to lipopolysaccharide • cellular response to transforming growth factor beta stimulus • negative regulation of long-term synaptic potentiation • negative regulation of extrinsic apoptotic signaling pathway in absence of ligand Sources: Amigo / QuickGO
RNA expression pattern
File:PBB GE CX3CR1 205898 at tn.png
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	1524	13051
Ensembl	ENSG00000168329	ENSMUSG00000052336
UniProt	P49238	Q9Z0D9
RefSeq (mRNA)	NM_001171171	NM_009987
RefSeq (protein)	NP_001164642	NP_034117
Location (UCSC)	Chr 3: 39.26 – 39.28 Mb	Chr 9: 119.9 – 120.07 Mb
PubMed search	[1]	[2]