Template:PBB/5008

Oncostatin M
PDB rendering based on 1evs.
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 1EVS
Identifiers
Symbols	OSM ; MGC20461
External IDs	OMIM: 165095 MGI: 104749 HomoloGene: 10741 GeneCards: OSM Gene
Gene ontology Molecular function • cytokine activity • oncostatin-M receptor binding • growth factor activity Cellular component • extracellular space • intracellular Biological process • positive regulation of acute inflammatory response • immune response • multicellular organismal development • peripheral nervous system development • cell proliferation • positive regulation of cell proliferation • negative regulation of cell proliferation • response to heat • positive regulation of peptidyl-serine phosphorylation • oncostatin-M-mediated signaling pathway • regulation of growth • tyrosine phosphorylation of Stat3 protein • tyrosine phosphorylation of Stat5 protein • tyrosine phosphorylation of Stat1 protein • positive regulation of tyrosine phosphorylation of Stat3 protein • positive regulation of MAPK cascade • negative regulation of meiotic nuclear division • positive regulation of transcription from RNA polymerase II promoter • negative regulation of hormone secretion • behavioral response to pain • positive regulation of peptidyl-tyrosine phosphorylation • positive regulation of cell division • positive regulation of apoptotic signaling pathway Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	5008	18413
Ensembl	ENSG00000099985	ENSMUSG00000058755
UniProt	P13725	P53347
RefSeq (mRNA)	NM_020530	NM_001013365
RefSeq (protein)	NP_065391	NP_001013383
Location (UCSC)	Chr 22: 30.26 – 30.27 Mb	Chr 11: 4.24 – 4.24 Mb
PubMed search	[1]	[2]