Tetrahydroberberine oxidase

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tetrahydroberberine oxidase
Identifiers
EC number 1.3.3.8
CAS number Template:CAS
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a tetrahydroberberine oxidase (EC 1.3.3.8) is an enzyme that catalyzes the chemical reaction

(S)-tetrahydroberberine + 2 O2 \rightleftharpoons berberine + 2 H2O2

Thus, the two substrates of this enzyme are (S)-tetrahydroberberine and O2, whereas its two products are berberine and H2O2.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with oxygen as acceptor. The systematic name of this enzyme class is (S)-tetrahydroberberine:oxygen oxidoreductase. This enzyme is also called (S)-THB oxidase. This enzyme participates in alkaloid biosynthesis.

References

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