Up-and-down procedure

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Lua error in package.lua at line 80: module 'strict' not found. Up-and-down procedure (or method) is an alternative to the LD50 acute toxicity test.[1][2]

It requires fewer animals to achieve similar accuracy as the LD50 test.[3] However, the U.S. Food and Drug Administration has begun to approve non-animal alternatives.[4][5]

References

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  1. Lua error in package.lua at line 80: module 'strict' not found.
  2. Lua error in package.lua at line 80: module 'strict' not found.
  3. Acute Oral Toxicity (AOT) Up-And-Down-Procedure
  4. Lua error in package.lua at line 80: module 'strict' not found.
  5. Lua error in package.lua at line 80: module 'strict' not found.