XPO5

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Exportin-5 (XPO5) is a protein that in humans is encoded by the XPO5 gene.[1][2][3]

Exportin-5 is a member of the karyopherin family.[3] In metazoa, it is involved in transport of pre-microRNA out of the nucleus, where such molecules are generated by the Microprocessor complex, and into the cytoplasm for further processing by the Dicer enzyme.[4][5][6][7]

The plant homolog is called HASTY; although it is known to be required for the miRNA biogenesis pathway, its role in nuclear export is less clear than it is in animals.[8]

Interactions

XPO5 has been shown to interact with ILF3[1] and Ran.[1]

References

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Further reading

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