Allylestrenol

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Allylestrenol
File:Allylestrenol.png
Systematic (IUPAC) name
(17β)-17-(prop-2-en-1-yl)estr-4-en-17-ol
Clinical data
Pregnancy
category
  • Used in threatened miscarriage and RPL
Identifiers
CAS Number 432-60-0 YesY
ATC code G03DC01 (WHO)
PubChem CID: 235905
DrugBank DB01431 YesY
ChemSpider 205855 YesY
UNII I47VB5DZ8O YesY
KEGG D01374 YesY
ChEMBL CHEMBL1445549 N
Synonyms 17α-Allylestr-4-en-17β-ol
Chemical data
Formula C21H32O
Molecular mass 300.48 g/mol
  • O[C@]2(CC[C@H]1[C@H]4[C@H](CC[C@@]12C)[C@@H]3\C(=C/CCC3)CC4)C\C=C
  • InChI=1S/C21H32O/c1-3-12-21(22)14-11-19-18-9-8-15-6-4-5-7-16(15)17(18)10-13-20(19,21)2/h3,6,16-19,22H,1,4-5,7-14H2,2H3/t16-,17+,18+,19-,20-,21-/m0/s1 YesY
  • Key:ATXHVCQZZJYMCF-XUDSTZEESA-N YesY
 NYesY (what is this?)  (verify)

Allylestrenol (BAN/INN), also known as allyloestrenol and allyl estrenol, is a synthetic progestogen used to prevent threatened miscarriage, recurrent pregnancy loss and premature labor.[1][2] In men, it has also been studied as a treatment for benign prostatic hyperplasia, with encouraging results.[3][4]

Allylestrenol is sold under several trade names, including Gestin, Turinal, Gestrenol, Gestanin, Gestanol or Gestanon, Maintaine, Orageston, and Profar. It is currently not marketed in the United States, United Kingdom, or Canada, but as of 2011, is extensively used in Bangladesh, Japan, Russia, India, and much of Southeast Asia.[1]

Allylestrenol is a 19-nortestosterone derivative.[5]

References

  1. ↑ 1.0 1.1 Lua error in package.lua at line 80: module 'strict' not found.
  2. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  3. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  4. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  5. ↑ Lua error in package.lua at line 80: module 'strict' not found.

External links


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