DNM1
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Dynamin-1 is a protein that in humans is encoded by the DNM1 gene.[1][2]
Function
This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.[3]
Interactions
DNM1 has been shown to interact with:
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References
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Wikimedia Commons has media related to Dynamin 1. |
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<references />, or <references group="..." />Further reading
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This article on a gene on human chromosome 9 is a stub. You can help Wikipedia by expanding it. |
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