Epithelial-myoepithelial carcinoma
From Infogalactic: the planetary knowledge core
| Epithelial-myoepithelial carcinoma | |
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Micrograph of an epithelial-myoepithelial carcinoma (right of image). The epithelial component has a tubular morphology and is evident only focally (upper left of image). Benign serous glands (parotid salivary gland) are also seen (left of image). H&E stain.
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| Classification and external resources | |
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| Patient UK | Epithelial-myoepithelial carcinoma |
Epithelial-myoepithelial carcinoma, abbreviated EMCa, is a rare malignant tumour that typically arises in a salivary gland and consists of both an epithelial and myoepithelial component. They are predominantly found in the parotid gland[1] and represent approximately 1% of salivary gland tumours.[2]
Diagnosis
EMCas are diagnosed by examination of tissue, e.g. a biopsy.
Its appearance is very similar to adenomyoepithelioma of the breast, which may be the same tumour at a different anatomical site.[3]
The histologic differential diagnosis includes adenoid cystic carcinoma and pleomorphic adenoma.
Prognosis
They generally have a good prognosis.[1] In one larger study, the 5-year and 10-year survival were over 90% and 80% respectively.[4]
See also
Additional images
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Epithelial-myoepithelial carcinoma - intermed mag.jpg
Intermed. mag.
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Epithelial-myoepithelial carcinoma - high mag.jpg
High mag.
