Mirogabalin

Mirogabalin

140px
Systematic (IUPAC) name
(1R,5S,6S)-6-(aminomethyl)-3-ethyl-bicyclo(3.2.0)hept-3-ene-6-acetic acid
Identifiers
CAS Number	1138245-21-2 Y
PubChem	CID: 49802951
ChemSpider	32701007
Chemical data
Formula	C12H19NO2
Molecular mass	209.285 g/mol
SMILES COC(=O)CC1(CN)CC2C1C=C(CC)C2
InChI InChI=1S/C12H19NO2/c1-2-8-3-9-5-12(7-13,6-11(14)15)10(9)4-8/h4,9-10H,2-3,5-7,13H2,1H3,(H,14,15)/t9-,10-,12-/m1/s1 Key:FTBQORVNHOIASH-CKYFFXLPSA-N

Mirogabalin (DS-5565) is a drug developed by Daiichi Sankyo and related to drugs such as gabapentin and pregabalin. Similarly to these drugs, mirogabalin binds to the α₂δ calcium channels (1 and 2), but with significantly higher potency than pregabalin. It has shown promising results in Phase II clinical trials for the treatment of diabetic peripheral neuropathic pain, and is currently in Phase III trials.

See also

• Atagabalin
• PD-217,014