Rosterolone

Rosterolone

Names
IUPAC name (1S,5S,8R,9S,10S,13S,14S,17S)-17-Hydroxy-1,10,13-trimethyl-17-propyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-one
Other names 17-Propylmesterolone; 17β-Hydroxy-1α-methyl-17α-propyl-5α-androstan-3-one
Identifiers
ChEMBL	ChEMBL2107498
ChemSpider	64367
EC Number	279-119-7
Jmol 3D model	Interactive image
MeSH	C041614
PubChem	71232
InChI InChI=1S/C23H38O2/c1-5-10-23(25)12-9-19-18-7-6-16-14-17(24)13-15(2)22(16,4)20(18)8-11-21(19,23)3/h15-16,18-20,25H,5-14H2,1-4H3/t15-,16-,18-,19-,20-,21-,22-,23-/m0/s1 Key: IMFNBOMNWHWKQD-MXENSADDSA-N InChI=1/C23H38O2/c1-5-10-23(25)12-9-19-18-7-6-16-14-17(24)13-15(2)22(16,4)20(18)8-11-21(19,23)3/h15-16,18-20,25H,5-14H2,1-4H3/t15-,16-,18-,19-,20-,21-,22-,23-/m0/s1 Key: IMFNBOMNWHWKQD-MXENSADDBK
SMILES CCC[C@@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3([C@H](CC(=O)C4)C)C)C)O
Properties
Chemical formula	C23H38O2
Molar mass	346.56 g·mol−1
Vapor pressure	{{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Rosterolone (INN) (developmental code name SH-434), also known as 17α-propylmesterolone, is a steroidal antiandrogen that was developed for topical administration but was never marketed. It has shown efficacy in the treatment of acne and in animal models lacks systemic effects with topical application.

See also

• Cioteronel
• Delanterone
• Inocoterone
• Mesterolone
• Topilutamide
• Topterone