SASS6

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Spindle assembly abnormal protein 6 homolog (SAS-6) is a protein that in humans is encoded by the SASS6 gene.[1][2][3]

Function

SAS-6 is necessary for centrosome duplication and functions during procentriole formation; SAS-6 functions to ensure that each centriole seeds the formation of a single procentriole per cell cycle.[4]

Clinical significance

Mutations in SASS6 are associated to MCPH .[5]

References

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Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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