DUSP16
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Dual specificity protein phosphatase 16 is an enzyme that in humans is encoded by the DUSP16 gene.[1][2][3][4]
The activation of mitogen-activated protein kinase (MAPK) cascades transduces various extracellular signals to the nucleus to induce gene expression, cell proliferation, differentiation, cell cycle arrest, and apoptosis. For full activation of MAPKs, dual-specificity kinases phosphorylate both threonine and tyrosine residues in MAPK TXY motifs. MKPs are dual-specificity phosphatases that dephosphorylate the TXY motif, thereby negatively regulating MAPK activity.[supplied by OMIM][4]
Interactions
DUSP16 has been shown to interact with MAPK14[5][6] and MAPK8IP1.[7]
References
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Further reading
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