Fontolizumab

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Fontolizumab
Monoclonal antibody
Type Whole antibody
Source Humanized (from mouse)
Target interferon gamma
Identifiers
CAS Number 326859-36-3 N
ATC code none
UNII 6J92H2439Z YesY
KEGG D04242 YesY
Chemical data
Molecular mass ca. 150 kDa
 NYesY (what is this?)  (verify)

Fontolizumab (planned trade name HuZAF) is a humanized monoclonal antibody[1] and an immunosuppressive drug for the treatment of auto-immune diseases like Crohn's disease.[2] A phase II clinical trial investigating the use for rheumatoid arthritis was terminated because the first phase did not meet the endpoint.[3]

References

  1. Statement On A Nonproprietary Name Adopted By The Usan Council - Fontolizumab, American Medical Association.
  2. Lua error in package.lua at line 80: module 'strict' not found.
  3. Clinical trial number NCT00281294 for "A Phase 2 Study to Evaluate the Safety, Tolerability, and Activity of Fontolizumab in Subjects With Active Rheumatoid Arthritis" at ClinicalTrials.gov


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