Ruplizumab

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Ruplizumab
Monoclonal antibody
Type Whole antibody
Source Humanized (from mouse)
Target CD154
Clinical data
Trade names Antova
Identifiers
CAS Number 220651-94-5 N
ATC code none
 NYesY (what is this?)  (verify)

Ruplizumab (trade name Antova) is a humanized monoclonal antibody intended for the treatment of rheumatic diseases like systemic lupus erythematosus and lupus nephritis. A study showed that the drug was associated with life-threatening thromboembolisms,[1] while another study only found thrombocytopenia.[2]

References

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