Rhodopsin kinase
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(Redirected from G protein-coupled receptor kinase 1)
| G protein-coupled receptor kinase 1 | |
|---|---|
| Identifiers | |
| Symbol | GRK1 |
| Alt. symbols | RHOK |
| Entrez | 6011 |
| HUGO | 10013 |
| OMIM | 180381 |
| RefSeq | NM_002929 |
| UniProt | Q15835 |
| Other data | |
| EC number | 2.7.11.14 |
| Locus | Chr. 13 q34 |
Rhodopsin kinase (EC 2.7.11.14, cone opsin kinase, G-protein-coupled receptor kinase 1, GPCR kinase 1, GRK1, GRK7, opsin kinase, opsin kinase (phosphorylating), rhodopsin kinase (phosphorylating), RK, STK14) is a serine/threonine-specific protein kinase involved in phototransduction.[1][2][3][4][5][6][7][8] This enzyme catalyses the following chemical reaction
- ATP + rhodopsin
ADP + phosphorhodopsin
Mutations in rhodopsin kinase are associated with a form of night blindness called Oguchi disease.[9]
See also
References
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<references />, or <references group="..." />External links
- Rhodopsin kinase at the US National Library of Medicine Medical Subject Headings (MeSH)
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