RPS6KA2

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Ribosomal protein S6 kinase alpha-2 is an enzyme that in humans is encoded by the RPS6KA2 gene.[1][2]

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine and threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.[2]

Interactions

RPS6KA2 has been shown to interact with MAPK3[3][4] and MAPK1.[3][4]

References

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Further reading

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