Setastine

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Setastine
File:Setastine.png
File:Setastine-3D-balls.png
Systematic (IUPAC) name
1-[2-[1-(4-chlorophenyl)-1-phenyl-ethoxy]ethyl]azepane
Identifiers
CAS Number 59767-13-4
PubChem CID: 43082
ChemSpider 39258
UNII 6G3OCF528J YesY
Chemical data
Formula C22H28ClNO
Molecular mass 357.92 g/mol
  • CC(C1=CC=CC=C1)(C2=CC=C(C=C2)Cl)OCCN3CCCCCC3

Setastine (Loderix) is an antihistamine used to treat allergies and rhinitis.[1][2]

Pharmacology

Pharmacodynamics

Setastine acts as a highly selective H1 receptor antagonist.[3] It has no anticholinergic, antiadrenergic, or antiserotonergic effects.

Pharmacokinetics

Setastine penetrates the blood-brain-barrier only weakly, hence, it is not sedating or is only mildly so.[3]

See also

References

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  3. ↑ 3.0 3.1 Lua error in package.lua at line 80: module 'strict' not found.
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