Tasosartan

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Tasosartan
Tasosartan.png
Systematic (IUPAC) name
2,4-dimethyl-8-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one
Clinical data
Pregnancy
category
  • N/A
Legal status
  • Withdrawn
Identifiers
CAS Number 145733-36-4 YesY
ATC code C09CA05 (WHO)
PubChem CID: 60919
IUPHAR/BPS 6898
DrugBank DB01349 YesY
ChemSpider 54890 N
UNII 48G92V856H YesY
Chemical data
Formula C23H21N7O
Molecular mass 411.459 g/mol
 NYesY (what is this?)  (verify)

Tasosartan is an angiotensin II receptor antagonist.

It was withdrawn from FDA review by the manufacturer after phase III clinical trials showed elevated transaminases (a sign of possible liver toxicity) in a significant number of participants given the drug.[1][2]

References

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