SCN4B

Sodium channel, voltage gated, type IV beta subunit
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 4MZ2, 4MZ3
Identifiers
Symbols	SCN4B ; ATFB17; LQT10; Navbeta4
External IDs	OMIM: 608256 MGI: 2687406 HomoloGene: 18384 ChEMBL: 4689 GeneCards: SCN4B Gene
Gene ontology Molecular function • voltage-gated sodium channel activity • sodium channel regulator activity • ion channel binding • voltage-gated sodium channel activity involved in cardiac muscle cell action potential Cellular component • voltage-gated sodium channel complex • intercalated disc • intrinsic component of plasma membrane Biological process • sodium ion transport • positive regulation of sodium ion transport • sodium ion transmembrane transport • cardiac muscle contraction • regulation of ventricular cardiac muscle cell membrane repolarization • cardiac muscle cell action potential involved in contraction • membrane depolarization during cardiac muscle cell action potential • AV node cell action potential • regulation of heart rate by cardiac conduction • regulation of sodium ion transmembrane transporter activity Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	6330	399548
Ensembl	ENSG00000177098	ENSMUSG00000046480
UniProt	Q8IWT1	Q7M729
RefSeq (mRNA)	NM_001142348	NM_001013390
RefSeq (protein)	NP_001135820	NP_001013408
Location (UCSC)	Chr 11: 118.13 – 118.15 Mb	Chr 9: 45.14 – 45.15 Mb
PubMed search	[1]	[2]

Sodium channel, also known as SCN4B is a protein which in humans is encoded by the SCN4B gene.

SCN4B is a sodium channel associated with long QT syndrome.

See also

• Sodium channel

External links

• GeneReviews/NIH/NCBI/UW entry on Romano-Ward Syndrome
• SCN4B protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)