CD79
Lua error in Module:Infobox at line 235: malformed pattern (missing ']'). Lua error in Module:Infobox at line 235: malformed pattern (missing ']'). CD79 (Cluster of Differentiation 79) is a transmembrane protein that forms a complex with the B-cell receptor (BCR) and generates a signal following recognition of antigen by the BCR. CD79 is composed of two distinct chains called CD79A and CD79B (formerly known as Ig-alpha and Ig-beta); these form a heterodimer on the surface of a B cell stabilized by disulfide bonding.[1] CD79a and CD79b are both members of the immunoglobulin superfamily. Human CD79a is encoded by the mb-1 gene that is located on chromosome 19, and CD79b is encoded by the B29 gene that located on chromosome 17.[1][2] Both CD79 chains contain an immunoreceptor tyrosine-based activation motif (ITAM) in their intracellular tails that they use to propagate a signal in a B cell, in a similar manner to CD3-generated signal tranduction observed during T cell receptor activation on T cells.[3]
References
- ↑ 1.0 1.1 Lua error in package.lua at line 80: module 'strict' not found.
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External links
- CD79 Antigens at the US National Library of Medicine Medical Subject Headings (MeSH)
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